Andrew Siwkowski: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Effect of dose and plasma concentration on liver uptake and pharmacologic activity of a 2′-methoxyethyl modified chimeric antisense oligonucleotide targeting PTEN

Richard S. Geary, Ed Wancewicz, John Matson, Megan Pearce, Andrew Siwkowski, Eric Swayze, Frank Bennett

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 324 KB

english, 2009

2

Discovery and Analysis of Antisense Oligonucleotide Activity in Cell Culture

Brenda F. Baker, Thomas P. Condon, Erich Koller, Robert A. McKay, Andrew M. Siwkowski, Timothy A. Vickers, Brett P. Monia

Journal:

Year:

2001

Language:

english

File:

PDF, 135 KB

english, 2001

3

Antisense Oligonucleotides Containing Conformationally Constrained 2′,4′-( N -Methoxy)aminomethylene and 2′,4′-Aminooxymethylene and 2′- O ,4′- C -Aminomethylene Bridged Nucleoside Analogues Show Improved Potency in Animal Models

Prakash, Thazha P., Siwkowski, Andrew, Allerson, Charles R., Migawa, Michael T., Lee, Sam, Gaus, Hans J., Black, Chris, Seth, Punit P., Swayze, Eric E., Bhat, Balkrishen

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.75 MB

english, 2010

4

An Exocyclic Methylene Group Acts As a Bioisostere of the 2′-Oxygen Atom in LNA

Seth, Punit P., Allerson, Charles R., Berdeja, Andres, Siwkowski, Andrew, Pallan, Pradeep S., Gaus, Hans, Prakash, Thazha P., Watt, Andrew T., Egli, Martin, Swayze, Eric E.

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

5

Peptide Nucleic Acids Conjugated to Short Basic Peptides Show Improved Pharmacokinetics and Antisense Activity in Adipose Tissue

Wancewicz, Edward V., Maier, Martin A., Siwkowski, Andrew M., Albertshofer, Klaus, Winger, Theodore M., Berdeja, Andres, Gaus, Hans, Vickers, Timothy A., Bennett, C. Frank, Monia, Brett P., Griffey, R

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.35 MB

english, 2010

6

Inhibition of HPV-16 E6/E7 Immortalization of Normal Keratinocytes by Hairpin Ribozymes

Luis M. Alvarez-Salas, Amy E. Cullinan, Andrew Siwkowski, Arnold Hampel and Joseph A. DiPaolo

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.55 MB

english, 1998

7

Mutational Analysis of Loops 1 and 5 of the Hairpin Ribozyme †

Shippy, Richard, Siwkowski, Andrew, Hampel, Arnold

Journal:

Year:

1998

Language:

english

File:

PDF, 140 KB

english, 1998

8

Evaluation of Basic Amphipathic Peptides for Cellular Delivery of Antisense Peptide Nucleic Acids

Maier, Martin A., Esau, Christine C., Siwkowski, Andrew M., Wancewicz, Edward V., Albertshofer, Klaus, Kinberger, Garth A., Kadaba, Neena S., Watanabe, Tanya, Manoharan, Muthiah, Bennett, C. Frank, Gr

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 202 KB

english, 2006

9

Short Antisense Oligonucleotides with Novel 2′−4′ Conformationaly Restricted Nucleoside Analogues Show Improved Potency without Increased Toxicity in Animals

Seth, Punit P., Siwkowski, Andrew, Allerson, Charles R., Vasquez, Guillermo, Lee, Sam, Prakash, Thazha P., Wancewicz, Edward V., Witchell, Donna, Swayze, Eric E.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 454 KB

english, 2009

10

Structure−Activity Relationship Study on a Simple Cationic Peptide Motif for Cellular Delivery of Antisense Peptide Nucleic Acid

Albertshofer, Klaus, Siwkowski, Andrew M., Wancewicz, Edward V., Esau, Christine C., Watanabe, Tanya, Nishihara, Kenji C., Kinberger, Garth A., Malik, Leila, Eldrup, Anne B., Manoharan, Muthiah, Geary

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 223 KB

english, 2005

11

Catalytic RNA. Series: Nucleic Acids and Molecular Biology, #10 Edited by Fritz Eckstein (Max-Planck-Institut) and David M. J. Lilley (University of Dundee). Springer: New York. 1996. xi + 417 pp. $197.00. ISBN 3-540-60795-1.

Siwkowski, Andrew, Hampel, Arnold

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 52 KB

english, 1997

12

Analysis of Hairpin Ribozyme Base Mutations in Loops 2 and 4 and Their Effects on cis -Cleavage in Vitro †

Siwkowski, Andrew, Shippy, Richard, Hampel, Arnold

Journal:

Year:

1997

Language:

english

File:

PDF, 287 KB

english, 1997

13

Catalytic Properties of Hairpin Ribozymes Derived from Chicory Yellow Mottle Virus and Arabis Mosaic Virus Satellite RNAs

DeYoung, Mary Beth, Siwkowski, Andrew M., Lian, Ying, Hampel, Arnold

Journal:

Year:

1995

Language:

english

File:

PDF, 2.28 MB

english, 1995

14

Configuration of the 5′-Methyl Group Modulates the Biophysical and Biological Properties of Locked Nucleic Acid (LNA) Oligonucleotides

Seth, Punit P., Allerson, Charles R., Siwkowski, Andrew, Vasquez, Guillermo, Berdeja, Andres, Migawa, Michael T., Gaus, Hans, Prakash, Thazha P., Bhat, Balkrishen, Swayze, Eric E.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.52 MB

english, 2010

15

Evaluation of C-5 Propynyl Pyrimidine-Containing Oligonucleotides In Vitro and In Vivo

Shen, Lijiang, Siwkowski, Andrew, Wancewicz, Edward V., Lesnik, Elena, Butler, Madeline, Witchell, Donna, Vasquez, Guillermo, Ross, Bruce, Acevedo, Oscar, Inamati, Gopal, Sasmor, Henri, Manoharan, Mut

Journal:

Antisense and Nucleic Acid Drug Development

Year:

2003

Language:

english

File:

PDF, 5.08 MB

english, 2003